Xeroderma or xerodermia, derived from the Greek words for "dry skin," is a condition involving the integumentary system, which in most cases can safely be treated with emollients and/or moisturizers. Xeroderma occurs most commonly on the scalp, lower legs, arms, the knuckles, the sides of the abdomen and thighs. Symptoms most associated with xeroderma are scaling (the visible peeling of the outer skin layer), itching and skin cracking. .