vascular endothelial growth factor

Vascular endothelial growth factor (VEGF) is an important signaling protein involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor.
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Factor /fac·tor/ an agent or element that contributes to the production of a result. accelerator factor coagulation f. V. [more]Vascular endothelial growth factor - Community and Resources

A gene that is responsible for the growth of blood vessels.

VEGF. A substance made by cells that stimulates new blood vessel formation.

A protein that can induce angiogenesis.