thalidomide

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thalidomide
n. drug formerly used as a sedative but found to cause severe birth defects


Wikipedia English The Free EncyclopediaDownload this dictionary
Thalidomide
Thalidomide is a sedativehypnotic, and multiple myeloma medication. The drug is a potent teratogen in rats, rabbits, non-human primates and humans.[1] Thalidomide was developed by German pharmaceutical company Grünenthal. It was sold from 1957 to 1961 in almost 50 countries under at least 40 names, including Distaval, Talimol, Nibrol, Sedimide, Quietoplex, Contergan, Neurosedyn, and Softenon. Thalidomide was chiefly sold and prescribed during the late 1950s and early 1960s to pregnant women, as an antiemetic to combat morning sickness and as an aid to help them sleep. Before its release inadequate tests were performed to assess the drug's safety, with catastrophic results for the children of women who had taken thalidomide during their pregnancies.
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WordNet 2.0 DictionaryDownload this dictionary
thalidomide
Noun
1. a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis
(hypernym) sedative-hypnotic, sedative-hypnotic drug


NCI Dictionary of Cancer Terms Download this dictionary
thalidomide
A drug that belongs to the family of drugs called angiogenesis inhibitors. It prevents the growth of new blood vessels into a solid tumor.

A Service of the National Cancer Institute.
Free English-Vietnamese DictionaryDownload this dictionary
thalidomide
thalidomide
danh từ thuốc giảm đau, thuốc an thần (được phát hiện 1961, khi các phụ nữ mang thai uống đã làm cho thai nhi biến dạng, dị tật)
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