thalidomide
n.
drug formerly used as a sedative but found to cause severe birth defects
Thalidomide
Thalidomide is a
sedative,
hypnotic, and
multiple myeloma medication. The drug is a potent
teratogen in rats, rabbits, non-human primates and humans.
[1] Thalidomide was developed by
German pharmaceutical company
Grünenthal. It was sold from 1957 to 1961 in almost 50 countries under at least 40 names, including Distaval, Talimol, Nibrol, Sedimide, Quietoplex, Contergan, Neurosedyn, and Softenon. Thalidomide was chiefly sold and prescribed during the late 1950s and early 1960s to
pregnant women, as an
antiemetic to combat
morning sickness and as an aid to help them sleep. Before its release inadequate tests were performed to assess the drug's safety, with catastrophic results for the children of women who had taken thalidomide during their pregnancies.
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thalidomide
Noun
1. a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis
(hypernym) sedative-hypnotic, sedative-hypnotic drug
thalidomide
A drug that belongs to the family of drugs called angiogenesis inhibitors. It prevents the growth of new blood vessels into a solid tumor.
thalidomide
thalidomide
danh từ thuốc giảm đau, thuốc an thần (được phát hiện 1961, khi các phụ nữ mang thai uống đã làm cho thai nhi biến dạng, dị tật)
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