TERT is an acronym for TElomerase Reverse Transcriptase, a
protein subgroup.
Telomerases are RNA-dependent
polymerases. However, despite their similarities to other RNA-dependent polymerases, telomerases are part of a distinct subgroup of proteins because they are so similar to each other even when they come from diverse organisms. To wit, telomerase lengthens telomeres in
DNA strands, thereby allowing senescent
cells that would otherwise become post-mitotic and commit
apoptosis to exceed the
Hayflick Limit and become potentially immortal, as is often the case with cancerous cells.
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