streptomycin

n. antibiotic used to treat tuberculosis and other bacterial infections

Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin stops bacterial growth by damaging cell membranes and inhibiting protein synthesis. Specifically, it binds to the 16S rRNA of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This prevents initiation of protein synthesis. Humans have structurally different ribosomes from bacteria, thereby allowing the selectivity of this antibiotic for bacteria. Streptomycin cannot be given orally, but must be administered by regular intramuscular injection. An adverse effect of this medicine is ototoxicity. It can result in permanent hearing loss.
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Streptomycin /strep·to·my·cin/ an aminoglycoside antibiotic produced by Streptomyces griseus and effective against a wide variety of aerobic [more]Streptomycin - Community and Resources

Noun
1. an antibiotic produced by the actinomycete Streptomyces griseus and used to treat tuberculosis
(hypernym) antibiotic, antibiotic drug

streptomycin /,steptou'maisin/
danh từ (dược học) Streptomyxin
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