selective serotonin reuptake inhibitor

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Selective serotonin reuptake inhibitor
"SSRI" redirects here; for other uses, see SSRI (disambiguation).Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants used in the treatment of depressionanxiety disorders, and some personality disorders. They are also typically effective and used in treating premature ejaculation problems.SSRIs increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, having little binding affinity for the noradrenaline and dopamine transporters.
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WordNet 2.0 DictionaryDownload this dictionary
selective-serotonin reuptake inhibitor
Noun
1. an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain
(synonym) SSRI
(hypernym) antidepressant, antidepressant drug
(hyponym) fluoxetine, Prozac



NCI Dictionary of Cancer Terms Download this dictionary
selective serotonin reuptake inhibitor
SSRI. A type of drug that is used to treat depression. SSRIs slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves.

A Service of the National Cancer Institute.

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