rebeccamycin

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Rebeccamycin
Rebeccamycin is a weak topoisomerase I inhibitor isolated from Streptomyces sp. structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50=500nM against P388 leukemia cells).
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iMedixDownload this dictionary
Rebeccamycin
Rebeccamycin Oncology An anticancer antibiotic and topoisomerase I inhibitor which may be of use in managing CA of the gallbladder. See Daunomycin. [more]Rebeccamycin - Community and Resources


NCI Dictionary of Cancer Terms Download this dictionary
rebeccamycin
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antineoplastic antibiotics.

A Service of the National Cancer Institute.

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