radioimmunotherapy

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Radioimmunotherapy
Radioimmunotherapy (RIT) utilizes an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues. By its nature, RIT requires a tumor cell to express an antigen that is unique to the neoplasm or is not accessible in normal cells.
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iMedixDownload this dictionary
Radioimmunotherapy
Radioimmunotherapy Immunology The use of radio-labeled–monoclonal antibodies that recognize specific antigens, and therefore concentrate in a [more]Radioimmunotherapy - Community and Resources


NCI Dictionary of Cancer Terms Download this dictionary
radioimmunotherapy
Treatment with a radioactive substance that is linked to an antibody that will attach to the tumor when injected into the body.

A Service of the National Cancer Institute.

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