prodrug

A prodrug is a pharmacological substance (drug) which is administered in an inactive (or significantly less active) form. Once administered, the prodrug is metabolised  in vivo into the active compound.
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Any medical compound designed to work only after the body, or a specific type of bodily tissue, has converted it. Prodrugs are useful when the “active” drug is too toxic for nonspecific or general distribution to bodily tissues, when absorption of the “active” drug is poor, or when the body breaks down the “active” drug prematurely. For example, a prodrug that only one type of enzyme can activate will work only in tissues that produce that enzyme. Such a prodrug can thus spare nontarget tissues toxic effects.

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