Pharmacological or biological activity is an expression describing the beneficial or adverse effects of a
drug on
living matter. When the drug is a complex chemical mixture, this activity is exerted by the substance's
active ingredient or
pharmacophore but can be modified by the other constituents. The main kind of biological activity is a substance's
toxicity. Activity is generally
dosage-dependent and it is not uncommon to have effects ranging from beneficial to adverse for one substance when going from low to high doses. Activity depends critically on fulfillment of the
ADME criteria.
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