oripavine
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Oripavine
Oripavine is an
opiate
and the major metabolite of
thebaine
. It is the prototypical molecule of a series of semi-synthetic
opioids
which includes
buprenorphine
. Although its analgesic potency is comparable to morphine, it is not used clinically due to its severe
toxicity
and low
therapeutic index
.
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