Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions.  Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so the synthesis of organic compounds has developed into one of the most important branches of organic chemistry. There are two main areas of research fields within the general area of organic synthesis: total synthesis and methodology.

Organic Syntheses is a scientific journal that since 1921 has provided the chemistry community with annual collections of detailed and checked procedures for the organic synthesis of organic compounds. The journal is peer reviewed. A unique feature of the review process is that all of the data and experiments reported in an article must be successfully repeated in the laboratory of a member of the Editorial Board as a check for reproducibility prior to publication.

La sintesi organica è la costruzione di molecole organiche attraverso processi chimici. Le molecole organiche hanno spesso un grado di complessità superiore ai composti inorganici, perciò la sintesi di composti organici è via via diventata uno dei più importanti aspetti della chimica organica. Le due grandi aree in cui è divisa la sintesi organica sono la sintesi totale e la metodologia.