ondansetron
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Ondansetron
Ondansetron (
INN
) (
IPA
: ) is a
serotonin
5-HT
3
receptor antagonist
used mainly to treat
nausea
and
vomiting
following
chemotherapy
. Its effects are thought to be on both peripheral and central nerves. One part is to reduce the activity of the
vagus nerve
, which is a nerve that activates the vomiting center in the
medulla oblongata
, the other is a blockage of serotonin receptors in the
chemoreceptor trigger zone
. It does not have much effect on vomiting that is due to motion sickness. This drug does not have any effect on
dopamine
receptors or
muscarinic receptor
s.
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This article uses material from
Wikipedia
®
and is licensed under the
GNU Free Documentation License
iMedix
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Ondansetron
Ondansetron /on·dan·se·tron/ an antiemetic used as the hydrochloride salt, in conjunction with cancer chemotherapy, radiotherapy, or after surgery. [
more
]
Ondansetron - Community and Resources
NCI Dictionary of Cancer Terms
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ondansetron
A drug that prevents or reduces nausea and vomiting. It belongs to the family of drugs called antiemetics.
A Service of the
National Cancer Institute
.
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