Noggin may mean:A carpentry term. A noggin, or
dwang is a short length of material, usually wood, inserted between two studs, joists, rafters or similar to brace a frame or to support a fixture. It is also the term for a brickwork infill-panel in timber frame construction. The article
dwang illustrates.A small drinking cup, often one made from wood and holding about ¼ of a pint. From this also a small drink, especially of an alcoholic liquor; ¼ pint. Example: "Many a noggin of whiskey is here quaffed..."A unit of liquid measure, usually now of alcohol, equal to one quarter of a
pint or a
gill, that is either 142mL if using
Imperial (British) pints or 118mL if using
US pints.A person's head, English slang usage, corruption of noggen, from Old Low Germanic noc by way of
Old English. Technically the latter term is always plural; compare to ox and oxen; brother and brethren, child and children, all of which retain Old English plural terminations. Example: "This thought kept chasing through our noggin." (New York Times).A lump of
cheese in
Black Country slang.A class of proteins. In biology,
noggin proteins are a class of proteins that are important in embryonic cellular differentiation.A famously strong ale brewed by
Charles Wells brewery of Bedford, England marketed as Noggin.A television network.
Noggin is a US television network for preschoolers and was a British children's' nostalgia channel.A book and television character.
Noggin the Nog is a character in the eponymous series of books and television programmes made by the UK company
Smallfilms.An abbreviation for the
Neuronal Oscillations Group in the Department of Physiology, Anatomy and Genetics at the
University of Oxford. Also known as the NOG and Paulsen Lab interested in the cellular basis of information processing in the mammalian brain.
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Noggin is a polypeptide that binds to members of the
TGF-β superfamily of
proteins. It is a
Bone morphogenetic protein inhibitor. Noggin plays a key role in neurulation by inhibiting
BMP4, along with other
morphogens such as
chordin and
follistatin and inducing the formation of the
neural plate. It plays a crucial role in bone development, by regulating the functions of BMP's. During the morphogenisis of organs such as the lungs, teeth and hair follicles, noggin helps to produce Lef1. Mouse knockout experiments show that noggin plays a role in neural tube fusion and joint formation.
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