nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are
ionotropic receptors
that form ligand gated
ion channels
in
cells'
plasma membranes
. Like the other type of
acetylcholine receptors
,
muscarinic acetylcholine receptors
(mAChRs), their opening is triggered by the
neurotransmitter
acetylcholine
(ACh), but they are also opened by
nicotine
. Also in contrast to muscarinic ACh receptors, nicotinic receptors do not operate with a
second messenger
, but open themselves forming an ion channel. Their action is inhibited by
curare
.
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Nicotinic acetylcholine receptor
Nicotinic /nic·o·tin·ic/ denoting the effect of nicotine and other drugs in initially stimulating and subsequently, in high doses, inhibiting neural [
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