nf-kappa b

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NF-kB
NF-κB (nuclear factor-kappa B) is a protein complex which is a transcription factor. NF-κB is found in all cell types and is involved in cellular responses to stimuli such as stress, cytokinesfree radicalsultraviolet irradiation, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection. Consistent with this role, incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseasesseptic shock, viral infection and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory.
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Wikipédia FrançaisDownload this dictionary
NF-kB
NF-κB pour nuclear factor-kappa B est une protéine de la super-famille des facteurs de transcription impliquée dans la réponse immunitaire et la réponse au stress cellulaire.
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Protéine NEMO (IKKg)
NEMO, pour NF-kB Essential Modulator est une sous-unité régulatrice d’une protéine kinase (IKK) impliquée dans la voie de signalisation des facteur de transcription NF-kB. Ultimement, cette cascade de signalisations jouera un rôle primordial dans la réponse immunitaire et inflammatoire, dans l’oncogénèse et dans la régulation de l’apoptose.
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NF-kappa B
NF-kappa B (Nuclear Factor kappa B), tüm hücre tiplerinde bulunan bir transkripsiyon faktörüdür. Sitoplazma içinde inaktif halde bulunur. Aktive olduğunda çekirdeğe taşınır.5 tipi bulunmaktadır: NF-κB1, NF-κB2, RelA (p65), RelA ve c-Rel.Bazı otoimmün hastalıklarda (örn. ülseratif kolit, Crohn) NF-kappa B'nin etkisi olduğu düşünülmektedir.
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