Neutrophil granulocytes, generally referred to as neutrophils, are the most abundant type of
white blood cells and form an integral part of the
immune system. Their name arrives from staining characteristics on
hematoxylin and
eosin (H&E) histological preparations. Whereas basophilic cellular components stain dark blue and eosinophilic components stain bright red, neutrophilic components stain a neutral pink. These
phagocytes are normally found in the
blood stream. However, during the
acute phase of
inflammation, particularly as a result of
bacterial infection, neutrophils leave the vasculature and migrate toward the site of inflammation in a process called
chemotaxis. They are the predominant cells in
pus, accounting for its whitish/yellowish appearance. Neutrophils react within an hour of tissue injury and are the hallmark of acute inflammation.
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