limit of detection

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Detection limit
In analytical chemistry, the detection limit, lower limit of detection, or LOD (limit of detection), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) within a stated confidence limit (generally 1%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.
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Limit of Detection (LOD)
The minimum concentration of a substance being analyzed test that has a 99 percent probability of being identified.

Provided as a public service by the U.S. Environmental Protection Agency

BioProcess International™ GlossaryDownload this dictionary
limit of detection
"Detection limit is the lowest concentration of analyte in a sample that can be detected, but not necessarily quantitated, under the stated experimental conditions".

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