leucovorin
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Folinic acid
Folinic acid (
INN
) or leucovorin (
USAN
), generally administered as calcium folinate (or leucovorin calcium), is an
adjuvant
used in
cancer
chemotherapy
involving the drug
methotrexate
. It is also used in
synergistic
combination with the chemotherapy agent
5-fluorouracil
.Folinic acid is not
folic acid
.
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®
and is licensed under the
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Leucovorin
Leucovorin /leu·co·vo·rin/ folinic acid ; the calcium salt is used as an antidote for folic acid antagonists, e.g. [
more
]
Leucovorin - Community and Resources
NCI Dictionary of Cancer Terms
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leucovorin
A drug used to protect normal cells from high doses of the anticancer drug methotrexate. It is also used to increase the antitumor effects of fluorouracil and tegafur-uracil, an oral treatment alternative to intravenous fluorouracil.
A Service of the
National Cancer Institute
.
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