lamotrigine

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Lamotrigine
Lamotrigine (marketed as Lamictal by GlaxoSmithKline, called Lamictin in South Africa, (Lamogine) in Israel, and in South Korea) is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown. Some think that it is a Na+ channel blocker. It is inactivated by hepatic glucuronidation.
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iMedixDownload this dictionary
Lamotrigine
Lamotrigine /la·mo·tri·gine/ an anticonvulsant used in the treatment of certain forms of epilepsy. lamotrigine, n brand name: Lamictal; drug class: [more]Lamotrigine - Community and Resources


NCI Dictionary of Cancer Terms Download this dictionary
lamotrigine
A drug that is used to help control some types of seizures. It is being studied in the prevention of peripheral neuropathy caused by some chemotherapy drugs. It belongs to the family of drugs called anticonvulsants.

A Service of the National Cancer Institute.

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