Isoleucine (abbreviated as Ile or I) is an α-
amino acid with the
chemical formula HO2CCH(NH2)CH(CH3)CH2CH3. It is an
essential amino acid, which means that humans cannot synthesize it, so it must be part of our diet. Its codons are AUU, AUC and AUA.With a hydrocarbon side chain, isoleucine is classified as a
hydrophobic amino acid. Together with
threonine, isoleucine is one of two common amino acids that have a
chiral side chain. Four
stereoisomers of isoleucine are possible, including two possible
diastereomers of L-isoleucine. However, isoleucine present in nature exists in one enantiomeric form, (2S,3S)-2-amino-3-methylpentanoic acid.
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((CH3)2CHCH(NH2)COOH) -amino-ß-methylvaleric acid].
A naturally occuring amino acid with a nonpolar side chain.