immunophenotyping

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Immunophenotyping
Immunophenotyping is a technique notably used in the diagnosis of leukemia. It involves the labelling of white blood cells with antibodies directed against surface proteins on their membrane. By choosing appropriate antibodies, the origin of leukemic cells can be accurately determined. The labelled cells are processed in a flow cytometer, a laser-based instrument capable of analyzing thousands of cells per second. The whole procedure can be performed on cells from the bloodbone marrow or spinal fluid in a matter of a few hours.
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Immunophenotyping
Immunophenotype /im·mu·no·phe·no·type/ a phenotype of cells of hematopoietic neoplasms defined according to their resemblance to normal T cells and [more]Immunophenotyping - Community and Resources


NCI Dictionary of Cancer Terms Download this dictionary
immunophenotyping
[IM-yoo-no-FEE-no-tie-ping]
A process used to identify cells, based on the types of antigens or markers on the surface of the cell. This process is used to diagnose specific types of leukemia and lymphoma by comparing the cancer cells to normal cells of the immune system.

A Service of the National Cancer Institute.

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