imipenem
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Imipenem
Imipenem is an
intravenous
beta-lactam
antibiotic
developed in
1985
. Imipenem belongs to the subgroup of
carbapenems
. It is derived from a compound called
thienamycin
, which is produced by the bacteria Streptomyces cattleya. Imipenem has a broad spectrum of activity against
aerobic
and
anaerobic
Gram positive
as well as
Gram negative
bacteria
. It is particularly important for its activity against
Pseudomonas aeruginosa
and the
Enterococcus
species. It is not active against
methicillin-resistant Staphylococcus aureus
, however. Imipenem and other drugs in the
carbapenem
class are commonly referred to as "magic bullets." Their use is typically restricted in order to avoid widespread bacterial resistance.
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Imipenem
Imipenem /im·i·pen·em/ a ß with a broad spectrum of activity against both gram-positive and gram-negative organisms. [
more
]
Imipenem - Community and Resources
NCI Dictionary of Cancer Terms
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imipenem
An antibiotic drug used to treat severe or very resistant infection. It belongs to the family of drugs called carbapenems.
A Service of the
National Cancer Institute
.
Define imipenem
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