gp120

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Gp120
gp120 is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons.The crystal structure of gp120 complexed to D1D2 CD4 and a neutralizing antibody Fab was solved by Peter Kwong in 1998. It is organized with an outer domain, an inner domain with respect to its termini and a bridging sheet. The gp120 gene is around 1.5Kb long and codes for around 500 amino acids. Three copies of gp120 form into a trimer that caps the end of gp41.
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Gp120
La GP120 est une glycoprotéine exprimée par le VIH (virus responsable du syndrome d'immunodéficience acquise ou SIDA)
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Humanes Immundefizienz-Virus
Das Humane Immundefizienz-Virus (HIV, engl.: Human immunodeficiency virus) – auch Menschliches Immunschwäche-Virus – ist ein  Virus, das zur Familie der Retroviren und zur Gattung der Lentiviren gehört. Eine Ansteckung führt nach einer unterschiedlich langen, meist mehrjährigen Inkubationsphase zu Aids (acquired immunodeficiency syndrome, erworbenes Immundefektsyndrom), einer derzeit noch unheilbaren Immunschwächekrankheit.
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Gp120
GP120 é uma glicoproteína capaz de se ligar simultaneamente ao receptor de menbrana CD4+ e ao CCR5 de linfócitos T auxiliadores.A GP120 está presente na camada mais externa do retrovírus do tipo VIH e é graças a esta proteína que o vírus é capaz de fundir sua membrana à da célula T, iniciando a sequência de contaminação.
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Gp120
Gp120, HIV virüsünün dış kapsülünde bulunan bir glikoproteindir. Son yıllarda, AIDS'e karşı alt ünite aşıların geliştirilmesinde bu proteinden yararlanılmaktadır.
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