fastidio

n. annoyance, trouble, bother, vexation, worry, nuisance, harassment, ado

n. annoyance, nuisance, bother; boredom

v. annoy, bother; tease; hassle

V
disdain; be scornful; feel aversion to| be squeamish

= annoyance, nuisance, aggravation, vexation, hassle, irritant, bummer.
Ex: False drops are perhaps less of an annoyance in a computer-based system when brief records can be quickly scanned and rejected as necessary.
Ex: However, delays in the generation of centralised records can be a considerable nuisance.
Ex: One reads, for instance, that a parameter in assessing the maximum period a user can be kept waiting is the 'aggravation quotient'.
Ex: Its absence from the ninth edition must have caused some vexation among cataloguers.
Ex: The article is entitled 'How to implement electronic subscriptions replacing the routing list hassle'.
Ex: Common factors affecting the quality of air in libraries include scents and other controllable irritants, dust mites, moulds and other inhaled substances associated with paper and books.
Ex: The article 'Bargains or bummers? Remainders' suggests that despite problems attaching to buying remainders, judicious purchasing of this stock can add valuable books to a library's collection at a very reasonable cost.

= irk, hassle, bug, bungle, spite, annoy, nag (at), niggle, grudge, gall, peeve.
Ex: She had been told from time to time that he seemed to derive satisfaction from needling the staff, but she had never been able to pin down specifically what he does that irks them.
Ex: Richins also included inconveniences such as special trips to complain, time and effort required to fill out form, being treated rudely, and having to hassle someone.
Ex: I have a question that has been bugging me since I upgraded to ProCite 5 some time ago.
Ex: Regrettably, the well-intentioned publication of Devereux's typescript has been incurably bungled, and Rastell remains without either a complete or trustworthy bibliography.
Ex: Men's abuse of children is in many instances instrumental in order to coerce or retaliate against women, echoing the Greek myth of Medea who killed her own children to spite her father.
Ex: Library pests are any humans, large or microscopic beasts, library equipment or installations, or chemical and biological substances that hamper or annoy the reader.
Ex: This a book that I had admired but that had nagged at me for years.
Ex: He was under the knife last week to treat the knee problem that has been niggling him.
Ex: He did not grudge them the money, but he grudged terribly the risk which the spending of that money might bring on them.
Ex: It was the American attitude of superiority that galled them the most.
Ex: Things like talking over the performances and cutting to commercials in the middle of performances were really peaving the people who watched.