An exon is any region of
DNA within a gene that is transcribed to the final
messenger RNA (mRNA) molecule, rather than being spliced out from the transcribed RNA molecule. Exons of many eukaryotic genes interleave with segments of non-coding DNA (
introns). The term exon was coined by American
biochemist Walter Gilbert in 1978: Function In many
genes, each exon contains part of the
open reading frame (ORF) that codes for a specific portion of the complete
protein. However, the term exon is often misused to refer only to coding sequences for the final protein. This is incorrect, since many noncoding exons are known in human genes (Zhang 1998).
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