A endothelin receptor antagonist (ERA) is a drug which blocks endothelin receptors. Two main kinds of ERAs exist: selective ERA (e.g. sitaxsentan), which affect endothelin A.dual ERAs,(e.g. bosentan) which affect both endothelin A and B .
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A drug that blocks the hormone endothelin and may prevent prostate cancer from spreading to the bones. It may also prevent the growth and spread of other types of cancer, including colorectal cancer.
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