Dynorphin is a class of
peptides produced by many different populations of
neurons, which has some
opiate-like activity. It is thus classed as an
endogenous opioid peptide. Dynorphin functions primarily as a
kappa opioid receptor agonist, meaning that it acts mainly at kappa opioid receptors. Other opioid peptides include
beta-endorphin,
met-enkephalin,
leu-enkephalin and
endomorphins. The dynorphins, which include
dynorphin A,
dynorphin B, alpha- and beta-neoendorphin, and
big dynorphin, are all the products of a single gene, 'preprodynorphin'.
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