Dope may refer to:

• Illegal drugs (commonly heroin, however, it may refer to cannabis, cocaine, opium, methamphetamine or other illegal drugs depending on exact region and time-period)
• An idiot
• Aircraft dope, a substance painted onto fabric-covered aircraft to tauten the skin
• Pipe dope, a slang term in plumbing for a chemical sealant applied to pipe threads to ensure a leakproof and pressure-tight seal
• Peg dope, a substance used to coat the bearing surfaces of the tuning pegs of string instruments
• Dope (TV series), an upcoming HBO drama series based on a Sara Gran novel of the same name
• Dope (band), an industrial metal band from Villa Park, Illinois.
  • Edsel Dope, the lead singer and rhythm guitarist of the band.
• Dope Couture, an up market street wear brand based in Los Angeles, California.
• The Straight Dope, a newspaper column
• Dopefish, a type of fish used as an in-joke in the Commander Keen universe and games made after
• Dopant, an impurity added to a substance to alter its properties
• Discrete optimized protein energy, a method of assessing homology models in protein structure prediction
• Information, usually not widely known. (American slang).
• DOPE (data on personal equipment, or data on previous engagement) book, used with sniper equipment
• Soft drink (American slang).

Dope can also be a slang term used to describe something such as "cool" or "awesome".

DOPE, or Discrete Optimized Protein Energy, is a statistical potential used to assess homology models in protein structure prediction. DOPE is based on an improved reference state that corresponds to noninteracting atoms in a homogeneous sphere with the radius dependent on a sample native structure; it thus accounts for the finite and spherical shape of the native structures. It is implemented in the popular homology modeling program MODELLER and used to assess the energy of the protein model generated through many iterations by MODELLER, which produces homology models by the satisfaction of spatial restraints. The models returning the minimum molpdfs can be chosen as best probable structures and can be further used for evaluating with the DOPE score. Like the current version of the MODELLER software, DOPE is implemented in Python and is run within the MODELLER environment. The DOPE method is generally used to assess the quality of a structure model as a whole. Alternatively, DOPE can also generate a residue-by-residue energy profile for the input model, making it possible for the user to spot the problematic region in the structure model.

See Döpe is a lake in the Nordwestmecklenburg district in Mecklenburg-Vorpommern, Germany. At an elevation of 38 m, its surface area is 0.77 km².

Das englische Wort Dope bezeichnet:

• eine Industrial-Rock-/Metal-Band aus New York, siehe Dope (Band)
• eine italienische Synth-Rock-Band, siehe Dope Stars Inc.
• eine deutsche Mountainbike Marke dope-cycles
• Illegale Drogen im Allgemeinen
• Cannabis im Speziellen

Döpe bezeichnet einen See und ein Naturschutzgebiet an der Nordseite des Schweriner Außensees in Mecklenburg-Vorpommern.

Dope est un groupe américain, fondé en 1997, de metal industriel originaire de New York dans le New Jersey.

Dope är ett metalband. Bandet bildades 1997 av bröderna Edsel och Simon Dope i södra Florida.

Dope - amerykański zespół muzyczny.