disease

n. sickness, illness

A disease is an abnormal condition of an organism that impairs bodily functions. In human beings, "disease" is often used more broadly to refer to any condition that causes discomfort, dysfunction, distress, social problems, and/or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories.
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Disease /dis·ease/ any deviation from or interruption of the normal structure or function of any body part, organ, or system that is manifested by a [more]Disease - Community and Resources

Noun
1. an impairment of health or a condition of abnormal functioning
(hypernym) illness, unwellness, malady, sickness
(hyponym) disease of the neuromuscular junction
(part-meronym) symptom

(v. t.)
To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
  

(v. t.)
To deprive of ease; to disquiet; to trouble; to distress.
  

(n.)
Lack of ease; uneasiness; trouble; vexation; disquiet.
  

(n.)
An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.