disaster

n. catastrophe, misfortune, calamity

A disaster (from Middle French désastre, from Old Italian disastro, from the Greek pejorative prefix dis- bad + aster star) is the impact of a natural or man-made hazards that negatively affects society or environment. The word disaster's root is from astrology: this implies that when the stars are in a bad position a bad event will happen.
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A spoof of disaster films, an asteroid is coming towards earth and Harry Bottoms is in charge of saving us all...again... Disaster! is made with clay mation.
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Disaster Public health Any unanticipated event that requires urgent response, bringing people and/or property out of harm's way in order to minimize [more]Disaster - Community and Resources

Noun
1. a state of extreme (usually irremediable) ruin and misfortune; "lack of funds has resulted in a catastrophe for our school system"; "his policies were a disaster"
(synonym) catastrophe
(hypernym) adversity, hardship, hard knocks
2. an event resulting in great loss and misfortune; "the whole city was affected by the irremediable calamity"; "the earthquake was a disaster"
(synonym) calamity, catastrophe, tragedy, cataclysm
(hypernym) misfortune, bad luck
(hyponym) act of God, force majeure, vis major, inevitable accident, unavoidable casualty
3. an act that has disastrous consequences
(hypernym) destruction, devastation

(v. t.)
To bring harm upon; to injure.
  

(v. t.)
To blast by the influence of a baleful star.
  

(n.)
An unpropitious or baleful aspect of a planet or star; malevolent influence of a heavenly body; hence, an ill portent.
  

(n.)
An adverse or unfortunate event, esp. a sudden and extraordinary misfortune; a calamity; a serious mishap.