A chemical substance is a material with a definite chemical composition. It is a
concept that became firmly established in the late eighteenth century after work by the chemist
Joseph Proust on the composition of some pure chemical compounds such as
basic copper carbonate. He deduced that: "All samples of a compound have the same composition; that is, all samples have the same proportions, by mass, of the elements present in the compound". This became known as the
law of constant composition. Later with the advancement of methods for
chemical synthesis particularly in the realm of
organic chemistry; the discovery of many more chemical elements and new techniques in the realm of
analytical chemistry used for isolation and purification of elements and compounds from chemicals that led to the establishment of modern
chemistry, the concept was defined as is found in most chemistry textbooks. However, there are some controversies regarding this definition mainly because the large number of chemical substances reported in chemistry literature need to be indexed.
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