carcinoembryonic antigen
n.
CEA, antigen found in an increased amount in the blood of people who suffer from certain cancers (such as colon cancer) or other diseases and in the blood of heavy smokers
Carcinoembryonic antigen
Carcinoembryonic antigen (CEA) is a
glycoprotein involved in
cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA was first identified in
1965 by
Phil Gold and
Samuel O. Freedman in human
colon cancer tissue extracts. It was found that
serum from individuals with colorectal, gastric, pancreatic, lung and breast
carcinomas had higher levels of CEA than healthy individuals.
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Carcinoembryonic antigen
carcinoembryonic antigen
[KAR-sin-o-EM-bree-ON-ik ANT-i-jun]
CEA. A substance that is sometimes found in an increased amount in the blood of people who have certain cancers, other diseases, or who smoke. It is used as a tumor marker for colorectal cancer.