Cacique (; ; feminine form: cacica), also cassique in archaic English, is a title derived from the Taíno word for the pre-Columbian chiefs or leaders of tribes in the Bahamas, Greater Antilles, and the northern Lesser Antilles. The Spanish, subsequent to encounters with the Taíno upon their arrival in the New World, used the word as a title for the leaders of the other indigenous tribes they encountered in the Western Hemisphere territories they occupied. In the Spanish language, both in Spain and Latin America, the term has come to mean a local political boss who exercises excessive power. The derivative term "Caciquismo" has been used to describe a democratic system subverted by the power of such local bosses successfully influencing the electoral process in their favour. It has been used most notably to refer to late nineteenth century Spain and twentieth century Mexico.

Kazike (sp.: cacique) ist eine Bezeichnung für indigene Stammesoberhäupter oder Adlige in Mittel- und Südamerika.

Cacique eller Cazique (femininum: Caciva) är en titel som kommer från taíno-befolkningen och är ett ord som betecknar de förcolumbianska ledarna i Bahamas, Stora Antillerna och Små Antillerna.

Cacique o cazique (italianizzato in cacicco) è un termine con cui si definivano tradizionalmente i capi di alcune comunità tribali in America latina. Ancora oggi viene usato in Messico per indicare il capo del villaggio. La parola originariamente apparteneva alla lingua dei taino (etnia caraibica appartenente al gruppo degli arawak).