cachexia

n. chronic weakness, debility (caused by illness)

Cachexia (pronounced ) is loss of weight, muscle atrophy, fatigue, weakness and significant loss of appetite in someone who is not actively trying to lose weight. It can be a sign of various underlying disorders; when a patient presents with cachexia, a doctor will generally consider the possibility of cancer, certain infectious diseases (e.g. tuberculosis, AIDS) and some autoimmune disorders. Cachexia physically weakens patients to a state of immobility stemming from loss of appetite, asthenia, and anemia, and response to standard treatment is usually poor.
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Cachexia /ca·chex·ia/ a profound and marked state of constitutional disorder; general ill health and malnutrition. [more]Cachexia - Community and Resources

Noun
1. any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease
(synonym) cachexy, wasting
(hypernym) infirmity, frailty, debility, feebleness, frailness

(n.)
Alt. of Cachexy