astrocytoma
n.
tumor which is composed of astrocytes and forms in the brain or nervous system (Medicine)
Astrocytoma
Astrocytomas are primary intracranial
tumors derived from
astrocytes cells of the brain. They may arise in the
cerebral hemispheres, in the
posterior fossa, in the
optic nerve, and rarely, the
spinal cord. The
WHO has given a four point scale depending on the histologic grade of the tumor (see below). This article focuses on the well-differentiated (Grade 2) astrocytoma. For grade 1 and 4 astrocytomas, see respective article headings: Pathogenesis Well-differentiated astrocytomas constitute about 25 to 30% of cerebral
gliomas. They have a predilection for the
cerebrum,
cerebellum,
hypothalamus,
pons, and
optic nerve and
chiasm. Although astrocytomas have many different histological characteristics, the most common type is the well-differentiated fibrillary astrocytoma. These tumors
express glial fibrillary acidic protein (GFAP), which possibly functions as a tumor suppressor, and is a useful diagnostic marker in a tissue biopsy.
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Astrocytoma
astrocytoma
noun
type of brain tumour, consisting of star-shaped cells which develop slowly in the brain and spinal cord
astrocytoma
[as-troe-sye-TOE-ma]
A tumor that begins in the brain or spinal cord in small, star-shaped cells called astrocytes.