antagonistic

adj. hostile, unfriendly

In literature, the antagonist is that against which the main character or protagonist contends. An antagonist is often a Villain, but may be a force of nature, set of circumstances, an animal, or other force that is in conflict with the protaganist.
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Adjective
1. indicating opposition or resistance
(synonym) counter
(similar) negative
2. characterized by antagonism or antipathy; "slaves antagonistic to their masters"; "antipathetic factions within the party"
(synonym) antipathetic, antipathetical
(similar) hostile
3. arousing animosity or hostility; "his antagonizing brusqueness"; "Europe was antagonistic to the Unites States"
(antonym) conciliatory, conciliative
(similar) alienating
4. used especially of drugs or muscles that counteract or neutralize each other's effect
(synonym) incompatible
(antonym) synergistic, interactive
5. opposing or neutralizing or mitigating an effect by contrary action
(synonym) counteractive
(similar) antacid
6. incapable of harmonious association
(similar) incompatible

(a.)
Alt. of Antagonistical
  

adj.
بپريت , بردھ , بمکھ , مخالف , خلاف , برعکس , ضد