Acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a form of
leukemia, or
cancer of the white blood cells.
Malignant, immature
white blood cells continuously multiply and are overproduced in the
bone marrow. ALL causes damage and death by crowding out normal cells in the bone marrow, and by spreading (
metastasizing) to other organs. ALL is most common in childhood and young adulthood with a peak incidence at 4-5 years of age, and another peak in old age. The overall cure rate in children is 85%, and about 50% of adults have long-term disease-free survival. 'Acute' refers to the undifferentiated, immature state of the circulating lymphocytes ("blasts"), and to the rapid progression of disease, which can be fatal in weeks to months if left untreated.
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Acute lymphocytic leukemia
acute lymphocytic leukemia
Noun
1. acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children
(synonym) acute lymphoblastic leukemia
(hypernym) acute leukemia
acute lymphocytic leukemia
[lim-fo-SIT-ik loo-KEE-mee-a]
ALL. A quickly progressing disease in which too many immature white blood cells (called lymphoblasts) are found in the blood and bone marrow. Also called acute lymphoblastic leukemia.