Acantholysis /acan·thol·y·sis/ dissolution of the intercellular bridges of the stratum spinosum of the epidermis.acantholyt´ic ac·an·thol·y·sis n. [more]Acantholysis - Community and Resources
Noun 1. a breakdown of a cell layer in the epidermis (as in pemphigus) (hypernym) skin disease, disease of the skin, skin disorder, skin problem, skin condition (part-holonym) pemphigus