Azithromycin is an
azalide, a subclass of
macrolide antibiotics. Azithromycin (brand names Zithromax® in Italy, United States and Portugal; Vinzam® / Zitromax® in Spain; Zmax®; Sumamed®; Aztrin®, Zitrocin®, Azibiot®, Azifine®) is one of the world's best-selling antibiotics, and is derived from
erythromycin; however, it differs chemically from
erythromycin in that a
methyl-substituted
nitrogen atom is incorporated into the
lactone ring, thus making the lactone ring 15-membered. Azithromycin is used to treat certain bacterial infections, most often bacteria causing
middle ear infections,
tonsillitis, throat infections,
laryngitis,
bronchitis,
pneumonia and
sinusitis. It is also effective against certain sexually transmitted infectious diseases, such as
non-gonococcal urethritis and cervicitis. Recent studies have also indicated it to be effective against late-onset asthma, but these findings are controversial and not widely accepted as of yet.
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