Xanthelasma (or xanthelasma palpebrarum) is a sharply demarcated yellowish collection of
cholesterol underneath the skin, usually on or around the
eyelids. Although not harmful or painful, these minor growths may be disfiguring and can be removed. The plural is "xanthelasmata". They are common in people of Asian extraction and those from the Mediterranean region. Xanthelasmata can be removed with
trichloroacetic acid peel, surgery,
lasers or
cryotherapy. Removal can cause scarring and pigment changes, but it is unusual after treatment with trichloroacetic acid. Because of the hereditary component, they may or may not indicate high blood levels of
cholesterol. Where there is no family history of xanthelasmata they usually indicate high cholesterol and may correlate with a risk of atheromatous disease (cholesterol building up in arteries). The root of the word is from Greek xanthos, ξανθος, "yellow".
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Tiny 1-2 mm yellowish plaques that are slightly raised on the skin surface of the upper or lower eyelids. Xanthelasma is caused by tiny deposits of fat in the skin and is often associated with abnormal blood fat levels (hyperlipidemia).
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