Amoxicillin (
INN) or amoxycillin (former
BAN) is a moderate-spectrum
β-lactam antibiotic used to treat bacterial
infections caused by susceptible
microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics. Amoxicillin is susceptible to degradation by
β-lactamase-producing bacteria, and so may be given with
clavulanic acid to decrease its susceptibility (see below). It was developed by
Beecham in 1972 and is currently marketed by
GlaxoSmithKline (the inheritor company) under the original trade name Amoxil.
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