Wegener's granulomatosis
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Wegener's granulomatosis
Wegener's granulomatosis is a form of
vasculitis
that affects the
lungs
,
kidneys
and other organs. Due to its end-organ damage, it can be a serious disease that requires long-term
immune suppression
. It is named after Dr.
Friedrich Wegener
who described the disease in
1936
.It is part of a larger group of vasculitic syndromes that all feature the presence for an abnormal type of circulating
antibody
termed
ANCA
s (antineutrophil cytoplasmic antibodies) and affect small and medium-sized
blood vessels
. Apart from Wegener's, it includes
Churg-Strauss syndrome
and
microscopic polyangiitis
.
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This article uses material from
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®
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