VEGF

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Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF) is an important signaling protein involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor.
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NCI Dictionary of Cancer Terms Download this dictionary
VEGF
Vascular endothelial growth factor. A substance made by cells that stimulates new blood vessel formation.
 
vascular endothelial growth factor
VEGF. A substance made by cells that stimulates new blood vessel formation.

A Service of the National Cancer Institute.

The Glossary of the American Council on Science and HealthDownload this dictionary
vascular endothelial growth factor (VEGF)
A protein that can induce angiogenesis.


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