Denaturation is the alteration of a
protein or
nucleic acid's shape through some form of external stress (for example, by applying
heat,
acid or
alkali), in such a way that it will no longer be able to carry out its cellular function. In biology, the shape and form of biological compounds such as proteins critically determine the function of the protein. Under stress, the shape and form (
protein structure and
protein folding) of the protein warp, and the protein changes (denatures) due to its inability to retain its old shape.
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