Taxol
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Paclitaxel
Paclitaxel is a
mitotic inhibitor
used in
cancer
chemotherapy
. It was discovered in a
National Cancer Institute
program at the
Research Triangle Institute
in 1967 when Monroe E. Wall and
Mansukh C. Wani
isolated it from the bark of the Pacific yew tree,
Taxus brevifolia
and named it 'taxol'. When it was developed commercially by
Bristol-Myers Squibb
(BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'Taxol®'.
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Taxol
Tax·ol A trademark for the drug paclitaxel. paclitaxel Warning - Hazardous drug! Onxol, Paxene, Taxol Pharmacologic class: Antimicrotubule agent [
more
]
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