Tacrolimus
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tacrolimus
n.
(Medicine) drug which helps to reduce and prevents the rejection of transplant of body organs and bone marrow transplants
Wikipedia English The Free Encyclopedia
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Tacrolimus
Tacrolimus (also FK-506 or Fujimycin) is an
immunosuppressive
drug
whose main use is after allogenic
organ transplant
to reduce the activity of the patient's
immune system
and so the risk of organ
rejection
. It is also used in a topical preparation in the treatment of severe
atopic dermatitis
("
eczema
"), severe refractory
uveitis
after
bone marrow
transplants, and the skin condition
vitiligo
. It is a 23-membered
macrolide
lactone
discovered in 1984 from the fermentation broth of a
Japanese
soil
sample that contained the
bacteria
Streptomyces tsukubaensis.
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Tacrolimus
Tacrolimus /tac·ro·li·mus/ a macrolide immunosuppressant having actions similar to those of cyclosporine ; used to prevent rejection of organ [
more
]
Tacrolimus - Community and Resources
NCI Dictionary of Cancer Terms
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tacrolimus
A drug used to help reduce the risk of rejection by the body of organ and bone marrow transplants.
A Service of the
National Cancer Institute
.
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