TPD

The Theory of Positive Disintegration (TPD) by Kazimierz Dabrowski describes a theory of personality and personality development. Unlike mainstream psychology, Dabrowski's theoretical framework views psychological tension, anxiety, and depression as necessary for growth. These "disintegrative" processes are therefore seen as "positive," whereas people who fail to go through positive disintegration may remain for their entire lives in a state of "negative integration," unquestioning and unaware. The strongest potential for tensions that lead to advancement through positive disintegration stem from mental overexcitabilities, above-average reactions to stimuli. Unlike some other theories of development such as Erikson's stages of psychosocial development, it is not assumed that even a majority of people progress through all levels. TPD is not a theory of stages, and levels do not correlate with age.
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Therapeutic Products Directorate (TPD) is a Canadian federal authority that regulates pharmaceutical drugs and medical devices for human use, a role performed by the Food and Drug Administration in the United States. Prior to being given market authorization, a manufacturer must present substantive scientific evidence of a product's safety, efficacy, and quality as required by the Food and Drugs Act and Regulations.
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Therapeutic Products Directorate (Canada) Responsible for the regulation — including evaluation and monitoring for safety, effectiveness, and quality — of pharmaceutical drugs, medical devices, and other therapeutic products available to Canadians.