The
selfish gene theory postulates that
natural selection will increase the frequency of those genes whose phenotypic effects ensure their successful
replication. Generally, a
gene achieves this goal by building, in cooperation with other genes, an
organism capable of transmitting the gene to descendants. Intragenomic conflict arises when genes inside a
genome are not transmitted by the same rules, or when a gene causes its own transmission to the detriment of the rest of the genome. (This last kind of gene is usually called selfish genetic element, or ultraselfish gene.)
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Violation of Mendel's first law which results in unequal segregation of a pair of alleles.
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