Simian immunodeficiency virus (SIV) is a
retrovirus that is found, in numerous strains, in
primates; the specific strains infecting
humans are
HIV-1 and
HIV-2, the viruses that cause
AIDS.The origin of HIV is now generally attributed to SIV from
African primates. HIV-2 is most closely related to SIVsm, the SIV strain that primarily infects
Sooty Mangabeys, while HIV-1 is closely related to the
chimpanzee strain of SIV, designated SIVcpz. The most likely route of transmission of HIV-1 to humans involves contact with the blood of chimps that are often hunted for bushmeat in Africa.
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